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The role of metabolic inflammation and stress in Alzheimer's pathogenesis.
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Summary of the study
Because current, therapeutic approaches to Alzheimer's disease (AD) remain disappointing, there is an urgent need for effective treatments. This study presents an overview of the emerging role of "metabolic inflammation" and stress as key factors in the pathogenesis of AD.
Based on recent findings and observations from an early pilot study, the presenters postulate a potential use of extracorporeal apheresis to prevent and treat Alzheimer's disease (AD).
Bornstein SR, Voit-Bak K, Rosenthal P, Tselmin S, Julius U, Schatz U, Boehm BO, Thuret S, Kempermann G, Reichmann H, Chrousos GP, Licinio J, Wong ML, Schally AV, Straube R. Extracorporeal apheresis therapy for Alzheimer disease-targeting lipids, stress, and inflammation. Mol Psychiatry. 2020 Feb;25(2):275-282. doi: 10.1038/s41380-019-0542-x. Epub 2019 Oct 8. PMID: 31595035.
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Further studies in connection with INUSpheresis® therapy
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